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British Journal of Anaesthesia, 2004, Vol. 92, No. 4 464-468
© 2004 The Board of Management and Trustees of the British Journal of Anaesthesia

Editorial III

Tissue oxygen tension (PTO2) in anaesthesia and perioperative medicine

J. Ragheb and D. J. Buggy

The first 150 words of the full text of this article appear below.

Tissue oxygen tension (PTO2) is the directly measured local partial pressure of oxygen in a specific tissue. It may be thought of as the local expression of global oxygen delivery (DO2) in a particular tissue. Tissue oxygen tension is the balance between oxygen perfusion and oxygen consumption in the tissue at a given time. In tissues with stable oxygen consumption, PTO2 reflects tissue perfusion more precisely than traditional clinical indices such as mean arterial pressure, cardiac output, urine output, skin temperature, or skin capillary refill.

Tissue oxygen tension may be measured in any tissue of interest, but values in peripheral subcutaneous tissue are the most widely reported. Its vascular bed is susceptible to vasoconstrictive influences, being the first vascular bed compromised when circulatory homeostasis is threatened and the last replenished during recovery.1 Subcutaneous tissue oxygen consumption is a relatively constant, low amount (approximately 1 . . . [Full Text of this Article]

Measurement techniques

Key role of anaesthesia in PTO2 and surgical wound healing

Regional anaesthesia

Other possible applications of PTO2

Summary


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